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Water quality. Determination of the estrogenic potential of water and waste water - Yeast estrogen screen (<i>Saccharomyces</i> <i>cerevisiae</i>) Ingestion-build-100998 The new specific colour dedicated1 Scope This document specifies a method for the determination of the estrogenic potential of water and waste water by means of a reporter gene assay with genetically modified yeast strains Saccharomyces cerevisiae. This reporter gene assay is based on the activation of the human estrogen receptor alpha. This method is applicable to: fresh water; waste water; aqueous extracts and leachates; eluates of sediments (fresh water); pore water; aqueous